Hexokinase 2 displacement from mitochondria-associated membranes prompts Ca2+-dependent death of cancer cells
A. Rasola, F. Ciscato, R. Filadi, I. Masgras, M. Pizzi, O. Marin, N. Damiano, P. Pizzo, A. Gori, F. Frezzato, L. Trentin, P. Bernardi
The paper shows that displacing HK2 from MAMs triggers Ca2+-dependent death of cancer cells, offering a potential anti-neoplastic strategy.
bioRxiv · Aug 15, 2019Cancer Biology