Rapid Sequential In Situ Multiplexing With DNA-Exchange-Imaging
Y. Wang, J. B. Woehrstein, N. Donoghue, M. Dai, M. S. Avendano, R. C. J. Schackmann, S. S. Wang, P. W. Tillberg, D. Park, S. W. Lapan, E. S. Boyden, J. S. Brugge, P. S. Kaeser, G. M. Church, S. S. Agasti, , P. Yin
This paper introduces DNA-Exchange-Imaging, a method for rapid, highly multiplexed in situ protein visualization, achieving sub-20 nm resolution and reducing imaging time from days to minutes.
bioRxiv · Mar 20, 2017Bioengineering