Sensitivity of human sweet taste receptor subunits T1R2 and T1R3 to activation by glucose enantiomers
N. Dubovski, Y. Ben-Shoshan Galezcki, E. Malach, M. Y. Niv
The paper investigates the sensitivity of human sweet taste receptor subunits T1R2 and T1R3 to activation by glucose enantiomers, finding that L-glucose activates them even without the counterpart monomer and identifying a key mutation affecting sensitivity.
bioRxiv · Dec 19, 2022Biochemistry