Author

M. Y. Niv

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

E. Malach· 3 shared N. Dubovski· 3 shared E. Margulis· 2 shared M. Behrens· 2 shared Y. Ben Shoshan-Galeczki· 2 shared A. Aronis· 1 shared A. Dagan-Wiener· 1 shared A. Oleszkiewicz· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersBiochemistry

E. Malach

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Sensitivity of human sweet taste receptor subunits T1R2 and T1R3 to activation by glucose enantiomers

N. Dubovski, Y. Ben-Shoshan Galezcki, E. Malach, M. Y. Niv

The paper investigates the sensitivity of human sweet taste receptor subunits T1R2 and T1R3 to activation by glucose enantiomers, finding that L-glucose activates them even without the counterpart monomer and identifying a key mutation affecting sensitivity.

bioRxiv · Dec 19, 2022Biochemistry

Subjective assessment and taste strips testing of gustatory function, at home, and in the lab

T. Green, A. Wolf, A. Oleszkiewicz, A. Aronis, T. Hummel, M. Y. Pepino, M. Y. Niv

The paper compares lab and home-based taste strips tests for gustatory function in healthy subjects, finding similar results between settings but no correlation between self-rated taste ability and test scores.

bioRxiv · Sep 11, 2022 · PreprintPhysiology

BitterMatch: Recommendation systems for matching molecules with bitter taste receptors

E. Margulis, Y. Slavutsky, T. Lang, M. Behrens, Y. Benjamini, M. Y. Niv

BitterMatch predicts ligand-receptor associations for bitter taste receptors with 80% precision and 42% recall using a hybrid recommendation system approach.

bioRxiv · Jan 13, 2022Biochemistry

Sweet chirality: the taste of L and D glucose stereoisomers

N. Dubovski, Y. Ben Shoshan-Galeczki, E. Malach, M. Y. Niv

The paper shows that both L and D glucose stereoisomers elicit similar sweet taste and activate the TAS1R2/TAS1R3 receptor, suggesting a framework for designing sweetener combinations.

bioRxiv · Aug 16, 2020Biochemistry

Intense bitterness of molecules: machine learning for expediting drug discovery

E. Margulis, A. Dagan-Wiener, R. S. Ives, S. Jaffari, K. Siems, M. Y. Niv

BitterIntense is a machine learning tool that predicts intense bitterness of molecules, helping to reduce drug development delays and animal use by identifying bitter compounds early.

bioRxiv · Jun 24, 2020Pharmacology & Toxicology

Sweet taste of heavy water

N. Ben Abu, P. E. Mason, H. Klein, N. Dubovski, Y. Ben Shoshan-Galeczki, E. Malach, V. Prazienkova, L. Maletinska, C. Tempra, V. C. Chamorro, J. Cvacka, M. Behrens, M. Y. Niv, P. Jungwirth

The paper shows humans can distinguish heavy water (D2O) from normal water by taste, mediated by the TAS1R2/TAS1R3 receptor, while mice cannot.

bioRxiv · May 22, 2020Biochemistry