A native chemical chaperone in the human eye lens
E. Serebryany, S. Chowdhury, C. N. Woods, D. C. Thorn, N. E. Watson, A. McClelland, R. E. Klevit, E. I. Shakhnovich
This study identifies myo-inositol as a chemical chaperone that suppresses lens crystallin aggregation, suggesting its potential as a therapeutic target for age-related cataracts.
bioRxiv · Dec 16, 2020Biophysics