LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion
C. Camillo, N. Facchinello, G. Villari, G. Mana, N. Gioelli, C. Sandri, M. Astone, D. Tortarolo, F. Clapero, D. Gays, R. E. Oberkersch, M. Arese, L. Tamagnone, D. Valdembri, M. M. Santoro, G. Serini
This study identifies LPHN2 as a regulator of endothelial cell adhesion and vascular permeability, showing it inhibits focal adhesion and promotes tight junctions, with implications for cancer metastasis.
bioRxiv · Apr 28, 2020Cell Biology