Single-molecule analysis of specificity and multivalency in binding of short linear substrate motifs to the APC/C
N. Hartooni, J. Sung, A. Jain, D. O. Morgan
The paper develops a single-molecule assay to study SLiM binding to APC/C and finds distinct affinities and multivalency in substrate recognition.
bioRxiv · Sep 25, 2021Biophysics