Polyamines and eIF5A hypusination facilitate SREBP2 translation and cholesterol synthesis to enhance enterovirus attachment and infection
M. R. Firpo, M. J. Petite, N. J. LoMascolo, P. Shah, B. C. Mounce
This study shows polyamines enhance CVB3 infection by promoting SREBP2 translation and cholesterol synthesis, linking polyamine and cholesterol homeostasis.
bioRxiv · Nov 1, 2021 · PreprintMicrobiology