Mycobacterium tuberculosis response to cholesterol is integrated with environmental pH and potassium levels via a lipid utilization regulator
Y. Chen, N. J. MacGilvary, S. Tan
The paper shows that Mtb's response to cholesterol, pH, and potassium is coordinated via the Mce3R regulator, with mce3R deletion reducing colonization in mice.
bioRxiv · Aug 22, 2023Microbiology