Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1.1
Y. E. El Ghaleb, N. J. Ortner, W. Posch, M. L. Fernandez-Quintero, W. E. Tuinte, S. Monteleone, H. J. Draheim, K. R. Liedl, D. Wilflingseder, J. Striessnig, P. Tuluc, B. E. Flucher, M. Campiglio
This study shows that the γ1 subunit reduces current density of CaV1.1a but not CaV1.1e, and this effect depends on alternative splicing of exon 29 in CaV1.1a.
bioRxiv · Nov 10, 2021 · PreprintPhysiology