Author

M. L. Fernandez-Quintero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. R. Loeffler· 3 shared K. R. Liedl· 2 shared A. B. Ward· 1 shared B. E. Flucher· 1 shared B. Greenhouse· 1 shared C. B. Bau· 1 shared C. Deane· 1 shared D. Wilflingseder· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

J. R. Loeffler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Broadly inhibitory antibodies against severe malaria virulence proteins

R. A. Reyes, S. S. R. Raghavan, N. K. Hurlburt, V. Introini, I. H. Kana, R. W. Jensen, E. Martinez-Scholze, M. Gestal-Mato, C. B. Bau, M. L. Fernandez-Quintero, J. R. Loeffler, J. A. Ferguson, W.-H. Lee, G. M. Martin, T. G. Theander, , T. Lavstsen

The paper identifies two human monoclonal antibodies that broadly inhibit PfEMP1's binding to EPCR, a key process in severe malaria pathogenesis.

bioRxiv · Jan 25, 2024Immunology

Learning high-dimensional reaction coordinates of fast-folding proteins using State Predictive Information Bottleneck and Bias Exchange Metadynamics

N. Pomarici, S. Mehdi, P. Quoika, S. Lee, J. R. Loeffler, K. Liedl, P. Tiwary, M. L. Fernandez-Quintero

This study uses AI and enhanced sampling to accelerate protein unfolding simulations by learning high-dimensional reaction coordinates from poor data.

bioRxiv · Jul 24, 2023 · PreprintBiophysics

PEP-Patch: Electrostatics in Protein-Protein Recognition, Specificity and Antibody Developability

F. Waibl, N. D. Pomarici, V. J. Hoerschinger, J. R. Loeffler, C. Deane, G. Georges, H. Kettenberger, M. L. Fernandez-Quintero, K. R. Liedl

PEP-Patch quantifies and visualizes protein electrostatic potential to analyze protease specificity, antibody-antigen recognition, and predict antibody pharmacokinetics.

bioRxiv · Jul 14, 2023 · PreprintBiophysics

Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1.1

Y. E. El Ghaleb, N. J. Ortner, W. Posch, M. L. Fernandez-Quintero, W. E. Tuinte, S. Monteleone, H. J. Draheim, K. R. Liedl, D. Wilflingseder, J. Striessnig, P. Tuluc, B. E. Flucher, M. Campiglio

This study shows that the γ1 subunit reduces current density of CaV1.1a but not CaV1.1e, and this effect depends on alternative splicing of exon 29 in CaV1.1a.

bioRxiv · Nov 10, 2021 · PreprintPhysiology