Author

N. J. Petela

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

K. A. Nasmyth· 2 shared M. Voulgaris· 2 shared A. Gonzalez Llamazares· 1 shared A. Kaushik· 1 shared B. Hu· 1 shared B.-G. Lee· 1 shared C. Percival· 1 shared J. B. Rafferty· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

K. A. Nasmyth

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Author profile →

2 papers

Recent·Most cited

Conformational dynamics of cohesin/Scc2 loading complex are regulated by Smc3 acetylation and ATP binding

A. Kaushik, T. Than, N. J. Petela, M. Voulgaris, C. Percival, P. Daniels, J. B. Rafferty, K. A. Nasmyth, B. Hu

This study identifies how Smc3 acetylation and ATP binding regulate the dynamic conformations of the cohesin/Scc2 complex during chromosome loading.

bioRxiv · Dec 4, 2022Biochemistry

ATP dependent DNA transport within cohesin: Scc2 clamps DNA on top of engaged heads while Scc3 promotes entrapment within the SMC-kleisin ring

J. E. Collier, B.-G. Lee, M. Brunet-Roig, S. Yatskevich, N. J. Petela, J. Metson, M. Voulgaris, A. Gonzalez Llamazares, J. Lowe, K. A. Nasmyth

The paper demonstrates that Scc2 clamps DNA in cohesin's E-S/E-K compartments while Scc3 facilitates DNA entrapment within the SMC-kleisin ring during DNA loop extrusion.

bioRxiv · Jun 3, 2020 · PreprintBiochemistry