Author

M. Voulgaris

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Approach:biophysical modeling· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:protein folding & dynamics· 2 Assay:ATAC-seq· 1 Assay:DNA methylation· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

K. A. Nasmyth· 3 shared N. J. Petela· 2 shared A. Gonzalez Llamazares· 1 shared A. Kaushik· 1 shared B. Hu· 1 shared B.-G. Lee· 1 shared C. Percival· 1 shared J. B. Rafferty· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBiochemistry

K. A. Nasmyth

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Conformational dynamics of cohesin/Scc2 loading complex are regulated by Smc3 acetylation and ATP binding

A. Kaushik, T. Than, N. J. Petela, M. Voulgaris, C. Percival, P. Daniels, J. B. Rafferty, K. A. Nasmyth, B. Hu

This study identifies how Smc3 acetylation and ATP binding regulate the dynamic conformations of the cohesin/Scc2 complex during chromosome loading.

bioRxiv · Dec 4, 2022Biochemistry

Formation of the clamped state by Scc2 and DNA overcomes the constraints imposed by zipping-up of the SMC coiled coils on cohesin's ATPase

M. Voulgaris, M. Srinivasan, K. A. Nasmyth

This study investigates how Scc2 and DNA clamping overcome coiled coil zipping-up constraints on cohesin's ATPase activity during loop extrusion.

bioRxiv · Jun 19, 2022 · PreprintBiochemistry

ATP dependent DNA transport within cohesin: Scc2 clamps DNA on top of engaged heads while Scc3 promotes entrapment within the SMC-kleisin ring

J. E. Collier, B.-G. Lee, M. Brunet-Roig, S. Yatskevich, N. J. Petela, J. Metson, M. Voulgaris, A. Gonzalez Llamazares, J. Lowe, K. A. Nasmyth

The paper demonstrates that Scc2 clamps DNA in cohesin's E-S/E-K compartments while Scc3 facilitates DNA entrapment within the SMC-kleisin ring during DNA loop extrusion.

bioRxiv · Jun 3, 2020 · PreprintBiochemistry