Author

N. J. Wagner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

J. E. Beam· 2 shared S. E. Rowe· 2 shared B. Conlon· 1 shared B. P. Conlon· 1 shared E. S. M. Bahnson· 1 shared J. C. Shook· 1 shared K.-Y. Lu· 1 shared V. G. Fowler· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

J. E. Beam

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Author profile →

2 papers

Recent·Most cited

Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus

J. E. Beam, N. J. Wagner, K.-Y. Lu, S. E. Rowe, B. P. Conlon

This study shows that S. aureus toxin activates the NLRP3 inflammasome in macrophages, leading to glucose limitation and antibiotic tolerance in the pathogen.

bioRxiv · Jan 22, 2022Microbiology

Macrophage-produced peroxynitrite induces antibiotic tolerance and supersedes intrinsic mechanisms of persister formation

J. E. Beam, N. J. Wagner, J. C. Shook, E. S. M. Bahnson, V. G. Fowler, S. E. Rowe, B. Conlon

This study shows that macrophage-produced peroxynitrite induces antibiotic tolerance in S. aureus, overriding intrinsic persister formation mechanisms observed in pure culture.

bioRxiv · May 20, 2021Microbiology