Author

N. Kamat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 3 Research Focus:host-pathogen & immune response· 2 Organism:E. coli· 1 Assay:electrophysiology· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1

Frequent Co-Authors

T. F. Gunnels· 3 shared J. A. Peruzzi· 2 shared J. N. Leonard· 2 shared L. E. Sant'Anna· 2 shared A. Lemley· 1 shared D. Baker· 1 shared D. M. Stranford· 1 shared H. I. Edelstein· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBioengineering

T. F. Gunnels

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions

J. A. Peruzzi, T. F. Gunnels, H. I. Edelstein, P. Lu, D. Baker, J. N. Leonard, N. Kamat

This study shows how engineering protein-lipid interactions can improve the loading and delivery of protein cargo into extracellular vesicles for therapeutic applications.

bioRxiv · Apr 29, 2023 · PreprintBioengineering

Enhancing functionalized liposome avidity to cells via lipid phase separation

T. Q. Vu, L. E. Sant'Anna, N. Kamat

This study shows that lipid phase separation in nanoparticles can enhance liposome binding to cancer cells by improving the spatial arrangement of targeting and PEG molecules.

bioRxiv · Oct 18, 2022 · PreprintBioengineering

Probing the force-from-lipid mechanism with synthetic polymers

M. L. Jacobs, J. Steinkühler, A. Lemley, M. J. Larmore, T. F. Gunnels, L. C. T. Ng, S. M. Cologna, P. G. DeCaen, N. Kamat

This study investigates how changes in membrane mechanical properties affect the activation of mechanosensitive channels using synthetic amphiphiles and molecular dynamics simulations.

bioRxiv · May 20, 2022 · PreprintBiophysics

Elucidating design principles for engineering cell-derived vesicles to inhibit SARS-CoV-2 infection

T. F. Gunnels, D. M. Stranford, R. E. Mitrut, N. Kamat, J. N. Leonard

This study evaluates cell-derived vesicles as decoy nanoparticles to inhibit SARS-CoV-2 infection, finding they are effective against multiple variants and manufacturing methods.

bioRxiv · Dec 4, 2021Bioengineering

Lipid phase separation in vesicles enhances TRAIL-mediated cytotoxicity

T. Vu, J. A. Peruzzi, L. E. Sant'Anna, N. Kamat

This study shows lipid phase separation on vesicles enhances TRAIL cytotoxicity by controlling protein density, with effects dependent on TRAIL receptor type.

bioRxiv · Oct 29, 2021Bioengineering