Promiscuous enzymes cooperate at the substrate level en route to lactazole A
A. A. Vinogradov, M. Shimomura, N. Kano, Y. Goto, H. Onaka, H. Suga
This study investigates the biosynthesis of lactazole A, revealing dynamic enzyme cooperation and kinetic control in thiopeptide assembly using an in vitro system.
bioRxiv · May 12, 2020Biochemistry