Author

N. Kosaisawe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

J. G. Albeck· 3 shared M. Pargett· 3 shared B. Sparta· 2 shared C. Teragawa· 2 shared B. L. Rocha-Gregg· 1 shared G. Yellen· 1 shared J. S. Brugge· 1 shared K. Distor· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCell Biology

J. G. Albeck

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Author profile →

3 papers

Recent·Most cited

Continuous sensing of nutrients and growth factors by the mTORC1-TFEB axis

B. Sparta, M. Pargett, N. Kosaisawe, J. G. Albeck

The paper investigates how mTORC1-TFEB signaling responds to nutrient and growth factor inputs at the single-cell level, revealing graded rather than binary responses.

eLife · Sep 12, 2023Peer-reviewedCell Biology

Cell-to-cell variability in AMPK activation reveals autonomous cycles in cellular energy balance

N. Kosaisawe, B. Sparta, M. Pargett, C. Teragawa, J. G. Albeck

The paper uses live-cell imaging to show that individual cells cycle through states of anabolism and catabolism, revealing dynamic energy balance and autonomous metabolic fluctuations.

bioRxiv · Sep 24, 2019 · PreprintCell Biology

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

J. G. Albeck, Y. P. Hung, C. Teragawa, M. Pargett, T. E. Gillies, M. Minguet, K. Distor, B. L. Rocha-Gregg, N. Kosaisawe, J. S. Brugge, G. Yellen

The paper investigates how Akt regulates glycolysis to maintain metabolic stability in proliferating human cells through single-cell dynamics analysis.

bioRxiv · Apr 11, 2017Biochemistry