Author

M. Pargett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 3 Assay:imaging· 2 Assay:fluorescence / live-cell microscopy· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

J. G. Albeck· 5 shared N. Kosaisawe· 3 shared B. Sparta· 2 shared C. Teragawa· 2 shared T. E. Gillies· 2 shared A. A. Zeki· 1 shared A. E. Davies· 1 shared A. R. Ram· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersCell Biology

J. G. Albeck

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Spatiotemporal Clusters of ERK Activity Coordinate Cytokine-induced Inflammatory Responses in Human Airway Epithelial Cells

N. L. DeCuzzi, D. Oberbauer, K. J. Chmiel, M. Pargett, J. M. A. Ferguson, D. Murphy, A. A. Zeki, J. G. Albeck

The paper shows pro-inflammatory cytokines induce SPREADs in human airway epithelial cells, correlating with barrier dysfunction, and that anti-inflammatory drugs suppress these SPREADs.

bioRxiv · Feb 3, 2024Cell Biology

Continuous sensing of nutrients and growth factors by the mTORC1-TFEB axis

B. Sparta, M. Pargett, N. Kosaisawe, J. G. Albeck

The paper investigates how mTORC1-TFEB signaling responds to nutrient and growth factor inputs at the single-cell level, revealing graded rather than binary responses.

eLife · Sep 12, 2023Peer-reviewedCell Biology

Cell-to-cell variability in AMPK activation reveals autonomous cycles in cellular energy balance

N. Kosaisawe, B. Sparta, M. Pargett, C. Teragawa, J. G. Albeck

The paper uses live-cell imaging to show that individual cells cycle through states of anabolism and catabolism, revealing dynamic energy balance and autonomous metabolic fluctuations.

bioRxiv · Sep 24, 2019 · PreprintCell Biology

Systems-level properties of EGFR/Ras/ERK signalling amplify local signals to generate gene expressionplasticity

A. E. Davies, T. E. Gillies, S. Siebert, M. Pargett, S. J. Tobin, A. R. Ram, C. Juliano, G. Quon, M. J. Bissell, J. G. Albeck

The paper shows that EGFR/Ras/ERK signaling in invasive breast cancer cells produces more dynamic and disordered ERK activity, leading to heterogeneous gene expression compared to non-malignant cells.

bioRxiv · Nov 9, 2018 · PreprintCancer Biology

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

J. G. Albeck, Y. P. Hung, C. Teragawa, M. Pargett, T. E. Gillies, M. Minguet, K. Distor, B. L. Rocha-Gregg, N. Kosaisawe, J. S. Brugge, G. Yellen

The paper investigates how Akt regulates glycolysis to maintain metabolic stability in proliferating human cells through single-cell dynamics analysis.

bioRxiv · Apr 11, 2017Biochemistry