Viral microRNA regulation of Akt is necessary for reactivation of Human Cytomegalovirus from latency in CD34+ hematopoietic progenitor cells and humanized mice
N. L. Diggins, A. H. Pham, J. Mitchell, C. J. Parkins, L. Slind, R. Turner, P. Caposio, J. A. Nelson, M. H. Hancock
This study shows that HCMV miRNAs downregulate Akt to promote reactivation from latency in CD34+ cells and humanized mice.
bioRxiv · May 24, 2024 · PreprintMicrobiology