Author

N. M. Amankulor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

J. H. Sussman· 2 shared J. Xu· 2 shared A. Angione· 1 shared A. C. Resnick· 1 shared A. C. Tarbay· 1 shared A. Cillo· 1 shared A. Duensing· 1 shared A. E. Baxter· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

J. H. Sussman

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2 papers

Recent·Most cited

All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis

A. Rao, X. Zhang, A. Cillo, J. H. Sussman, P. Sandlesh, A. C. Tarbay, A. N. Mallela, C. Cardello, K. Krueger, J. Xu, A. Li, J. Xu, J. Patterson, E. Akca, A. Angione, , N. M. Amankulor

This study shows that all-trans retinoic acid (ATRA) improves immune response in IDH-mutant gliomas by restoring the RA pathway, leading to tumor regression in mouse models and a clinical trial for human patients.

bioRxiv · Apr 9, 2024 · PreprintCancer Biology

A longitudinal single-cell and spatial multiomic atlas of pediatric high-grade glioma

J. H. Sussman, D. A. Oldridge, W. Yu, C.-H. Chen, A. M. Zellmer, J. Rong, A. Parvaresh-Rizi, A. Thadi, J. Xu, S. Bandyopadhyay, Y. Sun, D. Wu, C. E. Hunter, S. Brosius, K. J. Ahn, , K. Tan

This study creates a longitudinal multiomic atlas of pediatric high-grade glioma, revealing distinct tumor cell states and therapeutic targets not seen in adult glioblastoma.

bioRxiv · Mar 6, 2024Cancer Biology