Author

P. Sandlesh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Angione· 1 shared A. C. Tarbay· 1 shared A. Cillo· 1 shared A. Duensing· 1 shared A. Li· 1 shared A. N. Mallela· 1 shared A. Rao· 1 shared A. Safina· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Angione

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis

A. Rao, X. Zhang, A. Cillo, J. H. Sussman, P. Sandlesh, A. C. Tarbay, A. N. Mallela, C. Cardello, K. Krueger, J. Xu, A. Li, J. Xu, J. Patterson, E. Akca, A. Angione, , N. M. Amankulor

This study shows that all-trans retinoic acid (ATRA) improves immune response in IDH-mutant gliomas by restoring the RA pathway, leading to tumor regression in mouse models and a clinical trial for human patients.

bioRxiv · Apr 9, 2024 · PreprintCancer Biology

Prevention of chromatin destabilization by FACT is crucial for malignant transformation

P. Sandlesh, A. Safina, I. Goswami, L. Prendergast, S. Rosario, E. C. Gomez, J. Wanf, K. V. Gurova

The paper shows that FACT prevents chromatin destabilization in transformed cells, which is crucial for malignant transformation and survival.

bioRxiv · Dec 17, 2018Cell Biology