Author

N. M. Thielens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Chouquet· 1 shared A. J. Pinto· 1 shared C. Marsman· 1 shared I. Bally· 1 shared J. Hennicke· 1 shared J.-B. REISER· 1 shared L. Schwaigerlehner· 1 shared P.-P. Unger· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

A. Chouquet

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2 papers

Recent·Most cited

Biophysical characterization of the oligomeric states of recombinant Immunoglobulins type-M and their C1q binding kinetics by Biolayer Interferometry

A. Chouquet, A. J. Pinto, J. Hennicke, W. L. W. Ling, I. Bally, L. Schwaigerlehner, N. M. Thielens, R. Kunert, J.-B. REISER

This study characterizes the oligomeric states and C1q binding kinetics of recombinant IgMs using biophysical methods, showing they retain complement activation function similar to plasma-derived IgMs.

bioRxiv · Sep 30, 2021 · PreprintBioengineering

Soluble FAS Ligand directs human memory B cells towards antibody-secreting cells

S. D. van Asten, P.-P. Unger, C. Marsman, S. Bliss, T. Jorritsma, N. M. Thielens, S. M. van Ham, R. M. Spaapen

This study identifies soluble FAS ligand as a factor promoting memory B cell differentiation into antibody-secreting cells, linking it to autoimmunity and potential therapeutic targets.

bioRxiv · Dec 4, 2020Immunology