Targeting the DNM3OS / miR-199a~214 cluster for the treatment of fibroproliferative diseases
G. Savary, M. Buscot, E. Dewaeles, S. Diazzi, N. Nottet, E. Courcot, J. Fassy, K. Lebrigand, I. S. Henaoui, N. Martis, C. Van der Hauwaert, S. Leroy, L. Plantier, A. Paquet, C. L. Lino Cardenas, , N. Pottier
This study identifies DNM3OS as a key regulator of fibroblast activation via miRNAs, offering a therapeutic target for fibrotic diseases like IPF.
bioRxiv · Jan 4, 2018 · PreprintPathology