Lineage tracing of Notch1-expressing cells in intestinal tumours reveals a distinct population of cancer stem cells.
L. Mourao, G. Jacquemin, M. Huyghe, W. J. Nawrocki, N. Menssouri, N. Servant, S. Fre
The paper identifies Notch1-expressing cells in intestinal tumors as a distinct population of cancer stem cells with properties similar to intestinal stem cells but reduced Lgr5 expression.
bioRxiv · Jul 9, 2018Cancer Biology