Merkel Cell Polyomavirus Small Tumor Antigen Activates Matrix Metallopeptidase-9 Gene Expression for Cell Migration and Invasion
N. Nwogu, L. E. Ortiz, A. Whitehouse, H. J. Kwun
This study shows MCV sT activates MMP-9 expression via the LSD domain, promoting cell migration and invasion in MCC, suggesting MMP-9 as a therapeutic target.
bioRxiv · Mar 2, 2020Microbiology