Incomplete influenza A virus genomes are abundant but readily complemented during spatially structured viral spread
N. T. Jacobs, N. O. Onuoha, A. Antia, R. Antia, J. Steel, A. C. Lowen
The paper quantifies incomplete influenza A virus genomes (IVGs) and shows they require complementation for replication, but spatial structure facilitates this process, supporting viral spread but not transmission.
bioRxiv · Jan 23, 2019Microbiology