Cancer stem cell-derived extracellular vesicles preferentially target MHCII- macrophages and PD1+ T cells in the tumor microenvironment
P. Gonzalez-Callejo, Z. Guo, T. Ziglari, N. M. Claudio, N. Oshimori, J. Seras-Franzoso, F. Pucci
The paper identifies CSC-derived extracellular vesicles that target MHCII- macrophages and PD1+ T cells, suggesting combination therapies targeting these cells may reduce HNSCC recurrence.
bioRxiv · Apr 26, 2022Cancer Biology