Author

F. Pucci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

N. M. Claudio· 2 shared T. Ziglari· 2 shared A. Wanner· 1 shared D. Derrick· 1 shared D. Williams· 1 shared E. S. Nakayasu· 1 shared F. Borriello· 1 shared I. Zanoni· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersPathology

N. M. Claudio

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Sequential chromogenic immunohistochemistry: spatial analysis of lymph nodes identifies contact interactions between plasmacytoid dendritic cells and plasmablasts

N. M. Claudio, M.-T. Nguyen, A. Wanner, F. Pucci

This paper develops a novel scIHC analysis pipeline to study spatial interactions between plasmablasts and plasmacytoid dendritic cells in lymph nodes from head and neck cancer patients.

bioRxiv · Apr 13, 2023 · PreprintPathology

Senescent cell-derived extracellular vesicles inhibit cancer recurrence by coordinating immune surveillance

T. Ziglari, N. Calistri, J. M. Finan, D. Derrick, E. S. Nakayasu, M. Burnet, J. E. Kyle, M. W. Hoare, L. Heiser, F. Pucci

This study shows senescent cell-derived extracellular vesicles (senEVs) suppress tumor growth by coordinating immune surveillance, specifically by recruiting MHC-II+ antigen-presenting cells and activating CCR2+ TH17 cells.

bioRxiv · Jun 30, 2022Cancer Biology

Cancer stem cell-derived extracellular vesicles preferentially target MHCII- macrophages and PD1+ T cells in the tumor microenvironment

P. Gonzalez-Callejo, Z. Guo, T. Ziglari, N. M. Claudio, N. Oshimori, J. Seras-Franzoso, F. Pucci

The paper identifies CSC-derived extracellular vesicles that target MHCII- macrophages and PD1+ T cells, suggesting combination therapies targeting these cells may reduce HNSCC recurrence.

bioRxiv · Apr 26, 2022Cancer Biology

Gene expression profiling of lymph node sub-capsular sinus macrophages in cancer

F. Pucci, N. Claudio, P. Danilo

This study profiles gene expression in lymph node sub-capsular sinus macrophages in cancer, revealing increased Fc receptors and proteolytic enzymes in squamous cell carcinomas.

bioRxiv · Jan 14, 2021Immunology

The physical form of microbial ligands bypasses the need for dendritic cell migration to stimulate adaptive immunity

F. Borriello, R. Spreafico, V. Poli, J. Chou, N. Barrett, L. Lacanfora, M. Franco, L. Marongiu, Y. Iwakura, F. Pucci, M. Kruppa, Z. Ma, D. Williams, I. Zanoni

This study shows that soluble fungal polysaccharides are immunosilent in peripheral tissues but become potent immunogens in draining lymph nodes without requiring dendritic cell migration.

bioRxiv · Mar 3, 2020 · PreprintImmunology