Author

T. Ziglari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

F. Pucci· 2 shared D. Derrick· 1 shared E. S. Nakayasu· 1 shared J. E. Kyle· 1 shared J. M. Finan· 1 shared J. Seras-Franzoso· 1 shared L. Heiser· 1 shared M. Burnet· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

F. Pucci

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Senescent cell-derived extracellular vesicles inhibit cancer recurrence by coordinating immune surveillance

T. Ziglari, N. Calistri, J. M. Finan, D. Derrick, E. S. Nakayasu, M. Burnet, J. E. Kyle, M. W. Hoare, L. Heiser, F. Pucci

This study shows senescent cell-derived extracellular vesicles (senEVs) suppress tumor growth by coordinating immune surveillance, specifically by recruiting MHC-II+ antigen-presenting cells and activating CCR2+ TH17 cells.

bioRxiv · Jun 30, 2022Cancer Biology

Cancer stem cell-derived extracellular vesicles preferentially target MHCII- macrophages and PD1+ T cells in the tumor microenvironment

P. Gonzalez-Callejo, Z. Guo, T. Ziglari, N. M. Claudio, N. Oshimori, J. Seras-Franzoso, F. Pucci

The paper identifies CSC-derived extracellular vesicles that target MHCII- macrophages and PD1+ T cells, suggesting combination therapies targeting these cells may reduce HNSCC recurrence.

bioRxiv · Apr 26, 2022Cancer Biology