BiochemistrybioRxiv
ASSESSING TARGET SPECIFICITY OF THE SMALL MOLECULE INHIBITOR MARIMASTAT TO SNAKE VENOM TOXINS: A NOVEL APPLICATION OF THERMAL PROTEOME PROFILING
C. F. Smith, C. M. Modahl, D. Ceja-Galindo…·A. J. Saviola
This study uses Thermal Proteome Profiling and PISA to assess marimastat's specificity against snake venom toxins, identifying its targets and interactions with specific proteoforms.
DOI 10.1016/j.mcpro.2024.100779