GDF8 Contributes to the Adverse Effects of Liver Injury on Skeletal Muscle Homeostasis and Regeneration
A. E. Culver, M. J. Hamang, Y. Wang, E. White, S. Gawrieh, R. K. Vuppalanchi, N. P. Chalasani, G. Dai, B. C. Yaden
This study identifies GDF8 as a mediator of liver-muscle crosstalk that contributes to muscle atrophy in liver disease and shows that targeting GDF8 can reverse these effects.
bioRxiv · Apr 27, 2021 · PreprintPathology