Activin B Promotes the Initiation and Progression of Liver Fibrosis
Y. Wang, M. J. Hamang, A. E. Culver, H. Jiang, P. Kusumanchi, N. P. Chalasani, S. Liangpunsakul, B. Yaden, G. Dai
This study shows activin B promotes liver fibrosis initiation and progression by acting on hepatocytes and hepatic stellate cells, and its neutralization prevents and regresses fibrosis in mice.
bioRxiv · Apr 27, 2021Pathology