Y. Song

Urban soil microbiomes exhibit taxonomic and functional potential for enhanced contaminant cycling

The paper analyzes urban soil microbiomes to identify taxonomic and functional patterns linked to urbanization, revealing core microbial taxa and metabolic processes associated with urban environments.

Splenic follicular B cells promote adverse cardiac remodeling after myocardial infarction via MHC II-dependent antigen presentation.

This study shows splenic follicular B cells worsen heart failure after MI by presenting cardiac antigens via MHC II, promoting adverse cardiac remodeling.

Propiconazole and Tianfengsu Regulated the Growth, Flavor, and Nutrition of Brassica rapa by Brassinosteroid Pathway

This study examines how Propiconazole and Tianfengsu affect Brassica rapa growth, flavor, and nutrition through the brassinosteroid pathway, showing synergistic benefits when used together.

Seed tuber microbiome is a predictor of next-season potato vigor

The paper predicts next-season potato vigor based on seed tuber microbiome composition using a Random Forest model trained on microbiome and crop development data.

Viscoelastic Extracellular Matrix Enhances Epigenetic Remodeling and Cellular Plasticity

This study shows viscoelastic substrates enhance epigenetic remodeling and cellular plasticity in fibroblasts, improving reprogramming efficiency into neurons and pluripotent stem cells.

Integrated Short-TE and Hadamard-edited Multi-Sequence (ISTHMUS) for Advanced MRS

The paper evaluates the ISTHMUS MRS sequence for reproducibility and data quality in the HBCD study, finding improved T2 correction and reduced operator workload.

Interplay Between FoxM1 and Dab2 Promotes Endothelial Cell Responses in Diabetic Wound Healing

This study identifies Dab2 and FoxM1 as key regulators of endothelial dysfunction in diabetes, showing that restoring Dab2 improves angiogenesis and wound healing.

The transcription factor OsbZIP48 governs rice responses to zinc deficiency

This study identifies OsbZIP48 as a transcription factor critical for rice's response to zinc deficiency, showing it regulates zinc transporter genes through direct promoter binding.

Single Cell Spatial Transcriptomic Profiling Identifies a LINE1 Associated Disarrayed Immune Microenvironment in Hepatocellular Carcinoma

This study uses single cell spatial transcriptomics to show LINE1 repeat RNA expression in HCC correlates with a disorganized immune microenvironment and poor patient survival.

High-throughput Microfluidic 3D Outer Blood-Retinal Barrier Model in a 96-Well Format: Analysis of Cellular Interactions and Barrier Function in Retinal Health and Disease

Is M1-L121E a good mimic on microbial rhodopsin? A viewpoint from excited-state dynamics

This paper investigates the excited-state dynamics of a microbial rhodopsin mimic, M1-L121E, and finds it captures key features but shows distinct differences in photoreaction dynamics compared to natural rhodopsin.

Long-Term In Vivo Molecular Monitoring Using Aptamer-Graphene Microtransistors

This paper introduces AGMs for long-term in vivo molecular monitoring, demonstrating detection of dopamine and serotonin in blood and in vivo dopamine release in mice for over a week.

HyperPRI: A Dataset of Hyperspectral Images for Underground Plant Root Study

HyperPRI provides a dataset of hyperspectral and RGB images of underground plant roots for non-destructive analysis, showing that combining spectral and spatial data improves segmentation.

The origin, divergence and inter-subspecies hybridization of house mice (Mus musculus)

This study traces the origin, divergence, and hybridization of three house mouse subspecies using population genomic data, revealing divergence times and patterns of introgression across Eurasia.

Structural insights into abscisic acid exporter AtABCG25

The paper determines the structure of AtABCG25, an ABA exporter, revealing its mechanism of ABA binding and transport through cryo-EM.

RGS2 is an innate immune checkpoint for TLR4 and Gαq-mediated IFNγ generation and lung injury

This study shows RGS2 limits IFNγ production in alveolar macrophages by inhibiting TLR4-Gαq signaling, reducing lung injury in mice and correlating with ARDS patient data.

Quantitative Learning of Cellular Features From Single-cell Transcriptomics Data Facilitates Effective Drug Repurposing

This study introduces SuperFeat, a framework that uses single-cell transcriptomics data to identify drug targets by modeling adverse cellular states, validated in vitro and in vivo.

Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumor

This study identifies immune cell types and biomarkers in irMyocarditis using single-cell RNA sequencing and TCR analysis across heart, blood, and tumor tissues.

Stratification of enterochromaffin cells by single-cell expression analysis

This study identifies fourteen enterochromaffin cell clusters in the gut using single-cell transcriptomics and spatial analysis, revealing subtypes with distinct functional properties and a Piezo2+ population involved in colon motility.

Comparative single-nucleus RNA-seq analysis captures shared and distinct responses to beneficial and pathogenic microbes in roots

The paper uses single-nucleus RNA-seq to compare plant root responses to beneficial and pathogenic microbes, identifying triterpene biosynthesis as a novel response to pathogens.

Seed tuber imprinting shapes the next-generation potato microbiome

This study shows that seed tuber microbiomes are influenced by their production field and genotype, and these effects persist through storage and into the next generation, without direct vertical inheritance of specific microbes.

miRNA-encoded regulatory peptides modulate cadmium tolerance and accumulation in rice

This study identifies miPEP156e, a miRNA-encoded peptide in rice, which enhances cadmium tolerance by modulating ROS and Cd transporter genes.

Complex epistatic interactions between ELF3, PRR9, and PRR7 regulates the circadian clock and plant physiology

The paper investigates the genetic interactions between ELF3, PRR9, and PRR7 in Arabidopsis, revealing complex epistatic relationships affecting circadian rhythms and plant development.

Pancreatic Tumor-Derived Extracellular Vesicles Stimulate Schwann Cell Phenotype Indicative of Perineural Invasion via IL-8 Signaling

This study identifies pancreatic tumor-derived extracellular vesicles as inducers of Schwann cell activation via IL-8 signaling, promoting perineural invasion in pancreatic cancer.

Beclin1-Deficient Adipocytes Promote Tumor Progression by YAP/TAZ-dependent Adipocyte Transformation

This study shows that Beclin1-deficient adipocytes promote tumor progression via YAP/TAZ signaling, and inhibiting this pathway reduces tumor growth in mice.

Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels

This study evaluates the neuro-regenerative potential of adipose-derived stem cells in aligned collagen I hydrogels for peripheral nerve repair.

Apposed networks of interacting TCRs and BCRs exhibiting mosaicked CDR3 sequences made of fixed junctional motifs

The paper identifies two networks of TCRβ and IGH clonotypes with conserved CDR3 sequences associated with over 63 diseases, suggesting evolutionary-conserved primordial antigen receptors.

Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease

This study characterizes SARS-CoV-2 NSP15 endoribonuclease, identifies its allosteric properties, and discovers new allosteric sites for inhibitor development.

Selenium reduction of ubiquinone via SQOR suppresses ferroptosis

The paper shows selenium reduces ubiquinone to ubiquinol via SQOR, protecting against ferroptosis independently of selenoprotein production.

OsNLP4-OsD3 module integrates nitrogen-iron nutrient signals to promote rice tillering by repressing strigolactone signaling

The paper identifies a mechanism where OsNLP4 integrates nitrogen-iron signals to repress strigolactone signaling, promoting rice tillering and yield.