Author

N. Plesnila

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:mouse· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

F. Hellal· 3 shared I. Khalin· 3 shared A. Liesz· 2 shared A. Simats· 2 shared M. Dichgans· 2 shared M. MOLBAY· 2 shared O. Gokce· 2 shared S. Besson-Girard· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersBioengineering

F. Hellal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Innate immune memory after brain injury drives inflammatory cardiac dysfunction

A. Simats, S. Zhang, D. Messerer, J. Cao, F. Chong, S. Besson-Girard, O. Carofiglio, S. Filser, N. Plesnila, C. Braun, O. Gokce, M. Dichgans, K. Hatakeyama, B. Bonev, E. Beltran, , A. Liesz

This study identifies innate immune memory after brain injury as a driver of chronic cardiac dysfunction, showing that post-stroke epigenetic changes in myeloid cells lead to inflammation and fibrosis in the heart.

bioRxiv · Oct 4, 2023Immunology

Single-cell precision nanotechnology in vivo

M. MOLBAY, B. Kick, S. Zhao, M. I. Todorov, T.-L. Ohn, S. Roth, A. Simats, V. Singh, I. Khalin, C. Pan, H. Singh Bhatia, F. Hellal, R. Zeidler, A. Liesz, N. Plesnila, , A. Erturk

This study demonstrates DNA origami can be directed in vivo to target immune cells and cancer metastases, showing potential for precision drug delivery.

bioRxiv · Jul 24, 2023 · PreprintBioengineering

Multi-omics and 3D-imaging reveal bone heterogeneity and unique calvaria cells in neuroinflammation

Z. I. Kolabas, L. B. Kuemmerle, R. Perneczky, B. Foerstera, M. Buttner, O. S. Caliskan, M. Ali, Z. Rong, H. Mai, S. Hummel, L. M. Bartos, G. Biechele, A. Zatcepin, N. L. Albert, M. Unterrainer, , Brendel

The paper uses multi-omics and 3D-imaging to show that calvaria bone marrow has a distinct molecular profile and contributes to neuroinflammation.

bioRxiv · Dec 24, 2021 · PreprintCell Biology

Dynamic tracing using ultra-bright labelling and multi-photon microscopy identifies endothelial uptake of poloxamer-188 coated poly(lactic-co-glycolic acid)nano-carriers in vivo

I. Khalin, C. Severi, D. Heimburger, A. Wehn, F. Hellal, A. Reisch, A. Klymchenko, N. Plesnila

The paper develops highly fluorescent PLGA nanoparticles coated with PF-68 and uses in vivo imaging to show their uptake by endothelial cells in the brain and peripheral organs.

bioRxiv · Nov 19, 2020Bioengineering