Author

O. Carofiglio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Liesz· 2 shared J. Cao· 2 shared S. Zhang· 2 shared A. Dutsch· 1 shared A. Kopczak· 1 shared A. Simats· 1 shared B. Bonev· 1 shared C. Braun· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

A. Liesz

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Innate immune memory after brain injury drives inflammatory cardiac dysfunction

A. Simats, S. Zhang, D. Messerer, J. Cao, F. Chong, S. Besson-Girard, O. Carofiglio, S. Filser, N. Plesnila, C. Braun, O. Gokce, M. Dichgans, K. Hatakeyama, B. Bonev, E. Beltran, , A. Liesz

This study identifies innate immune memory after brain injury as a driver of chronic cardiac dysfunction, showing that post-stroke epigenetic changes in myeloid cells lead to inflammation and fibrosis in the heart.

bioRxiv · Oct 4, 2023Immunology

Stroke induces early recurrent vascular events by inflammasome-dependent atherosclerotic plaque rupture

J. Cao, S. Roth, S. Zhang, A. Kopczak, M. K. Georgakis, X. Li, A. Dutsch, T. G. Liman, M. Endres, D. Brough, J. P. Green, S. R. Wernsdorf, C. Fürle, O. Carofiglio, J. Zhu, , A. Liesz

This study shows stroke triggers inflammasome-dependent atherosclerotic plaque rupture, leading to recurrent stroke, and identifies DNA-mediated inflammasome activation as a therapeutic target.

bioRxiv · Feb 1, 2023 · PreprintImmunology