Author

R. Zeidler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Erturk· 2 shared C. Pan· 2 shared K. Gaertner· 2 shared M. I. Todorov· 2 shared A. Ghasemi· 1 shared A. K. Schuetz· 1 shared A. Liesz· 1 shared A. Parra-Damas· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBioengineering

A. Erturk

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The nuclear speckles protein SRRM2 is a new therapeutic target molecule on the surface of cancer cells

M. Kellner, J. Hoermann, S. Fackler, H. Yuanyu, L. Lin, I. Ilik, T. Aktas, R. Feederle, S. M. Hauck, O. Gires, K. Gaertner, L. Lietao, R. Zeidler

The paper identifies SRRM2 as a surface-exposed cancer target and shows its utility in CAR-T cell therapy.

bioRxiv · Apr 26, 2024 · PreprintCancer Biology

Single-cell precision nanotechnology in vivo

M. MOLBAY, B. Kick, S. Zhao, M. I. Todorov, T.-L. Ohn, S. Roth, A. Simats, V. Singh, I. Khalin, C. Pan, H. Singh Bhatia, F. Hellal, R. Zeidler, A. Liesz, N. Plesnila, , A. Erturk

This study demonstrates DNA origami can be directed in vivo to target immune cells and cancer metastases, showing potential for precision drug delivery.

bioRxiv · Jul 24, 2023 · PreprintBioengineering

Micro RNAs are minor constituents of extracellular vesicles and are hardly delivered to target cells

M. Albanese, Y.-F. A. Chen, C. Huels, K. Gaertner, T. Tagawa, E. Mejias-Perez, O. T. Keppler, C. Goebel, R. Zeidler, M. Shein, A. K. Schuetz, W. Hammerschmidt

This study investigates whether extracellular vesicles (EVs) deliver microRNAs to target cells and found that miRNAs are not effectively delivered or functional.

bioRxiv · May 20, 2020Cell Biology

Deep learning reveals cancer metastasis and therapeutic antibody targeting in whole body

C. Pan, O. Schoppe, A. Parra-Damas, R. Cai, M. I. Todorov, G. Gondi, B. von Neubeck, A. Ghasemi, M. A. Reimer, J. Coronel, B. K. Garvalov, B. Menze, R. Zeidler, A. Erturk

This paper introduces DeepMACT, a pipeline for automated detection of cancer metastases and therapeutic antibody targeting in whole-body mouse models using deep learning and enhanced imaging.

bioRxiv · Feb 5, 2019 · PreprintCancer Biology