Author

N. R. James

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. D. Beale· 2 shared A. Zeng· 2 shared J. S. O'Neill· 2 shared N. M. Rzechorzek· 2 shared S. Y. Peak-Chew· 2 shared A. L. Edmondson· 1 shared A. Mihut· 1 shared C. Ellis· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

A. D. Beale

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2 papers

Recent·Most cited

A cellular basis for the mammalian nocturnal-diurnal switch

A. D. Beale, M. J. Christmas, N. M. Rzechorzek, A. Mihut, A. Zeng, C. Ellis, N. R. James, N. J. Smyllie, V. Pilorz, R. Richardson, M. F. Bertelsen, S. V. Fazal, Z. Voysey, K. Moreau, J. Pelletier, , J. S. O'Neill

The paper identifies a conserved cell-intrinsic signal inversion that enables the transition from nocturnality to diurnality, with mTOR signaling as a central mediator.

bioRxiv · Jun 22, 2023 · PreprintCell Biology

Circadian regulation of macromolecular complex turnover and proteome renewal

E. Seinkmane, A. L. Edmondson, S. Y. Peak-Chew, A. Zeng, N. M. Rzechorzek, N. R. James, J. A. West, J. Munns, D. C. Wong, A. D. Beale, J. S. O'Neill

This study investigates circadian regulation of protein turnover and proteome renewal, finding that synthesis and degradation rhythms consolidate proteome renewal while minimizing compositional changes.

bioRxiv · Sep 30, 2022Cell Biology