Author

J. A. West

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Organism:human· 1

Frequent Co-Authors

A. D. Beale· 1 shared A. L. Edmondson· 1 shared A. Zeng· 1 shared B. Liu· 1 shared C. Van den Haute· 1 shared D. C. Wong· 1 shared E. Legchenko· 1 shared E. Seinkmane· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

A. D. Beale

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ATP13A3 Variants Promote Pulmonary Arterial Hypertension by Disrupting Polyamine Transport

B. Liu, M. Azfar, E. Legchenko, J. A. West, S. Martin, C. Van den Haute, V. Baekelandt, J. Wharton, L. Howard, M. Wilkins, P. Vangheluwe, N. W. Morrell, P. D. Upton

This study identifies ATP13A3 as a polyamine transporter whose deficiency leads to endothelial dysfunction and pulmonary arterial hypertension.

bioRxiv · Aug 29, 2023 · PreprintCell Biology

Circadian regulation of macromolecular complex turnover and proteome renewal

E. Seinkmane, A. L. Edmondson, S. Y. Peak-Chew, A. Zeng, N. M. Rzechorzek, N. R. James, J. A. West, J. Munns, D. C. Wong, A. D. Beale, J. S. O'Neill

This study investigates circadian regulation of protein turnover and proteome renewal, finding that synthesis and degradation rhythms consolidate proteome renewal while minimizing compositional changes.

bioRxiv · Sep 30, 2022Cell Biology

Amitosis confers benefits of sex in the absence of sex to Tetrahymena

H. Zhang, J. A. West, R. A. Zufall, R. B. R. Azevedo

This study shows that amitosis in Tetrahymena provides evolutionary benefits similar to sex, enabling long-term success of asexual lineages by reducing mutation load and accelerating adaptation.

bioRxiv · Jun 10, 2021 · PreprintEvolutionary Biology