NanoFAST: Structure-based design of a small fluorogen-activating protein with only 98 amino acids
K. S. Mineev, S. A. Goncharuk, M. V. Goncharuk, N. V. Povarova, N. S. Baleeva, A. Y. Smirnov, I. N. Myasnyanko, D. A. Ruchkin, S. Bukhdruker, A. Remeeva, A. Mishin, V. Borshchevskiy, V. Gordeliy, A. S. Arseniev, D. A. Gorbachev, , M. S. Baranov
The paper designs a small fluorogen-activating protein (nanoFAST) by truncating FAST based on structural analysis, resulting in the shortest known genetically encoded tag with 98 amino acids.
bioRxiv · Dec 29, 2020Biochemistry