Author

S. A. Goncharuk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Organism:human· 1 Organism:plant (other)· 1 Research Focus:protein design· 1

Frequent Co-Authors

K. S. Mineev· 4 shared A. S. Arseniev· 3 shared M. L. Franco· 2 shared M. Vilar· 2 shared A. Benito-Martinez· 1 shared A. Cattaneo· 1 shared A. G. Savitskaya· 1 shared A. Mishin· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

K. S. Mineev

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural Basis for the transmembrane signaling and antidepressant-induced activation of the receptor tyrosine kinase TrkB

E. F. Kot, S. A. Goncharuk, M. L. Franco, A. S. Arseniev, A. Benito-Martinez, M. Costa, A. Cattaneo, M. Vilar, K. S. Mineev

This study determines the structure of the TrkB transmembrane domain using NMR and shows how fluoxetine activates the receptor by binding to it.

bioRxiv · Jun 6, 2023Biochemistry

Structural basis for the ligand promiscuity of the neofunctionalized, carotenoid-binding fasciclin domain protein AstaP

F. D. Kornilov, Y. B. Slonimskiy, D. A. Lunegova, N. A. Egorkin, A. G. Savitskaya, S. Y. Kleymenov, E. G. Maksimov, S. A. Goncharuk, K. S. Mineev, N. N. Sluchanko

This paper determines the structure of AstaP, a carotenoid-binding protein, and explains its ligand promiscuity through structural and biochemical analyses.

bioRxiv · Dec 26, 2022 · PreprintBiochemistry

Neurotrophin signaling is modulated by specific transmembrane domain interactions

M. L. Franco, K. D. Nadezhdin, T. P. Light, S. A. Goncharuk, A. Soler-Lopez, F. Ahmed, K. S. Mineev, K. Hristova, A. S. Arseniev, M. Vilar

The paper identifies and characterizes the direct interaction between TrkA and p75 through their transmembrane domains, showing its role in TrkA activation and cell differentiation.

bioRxiv · May 24, 2021 · PreprintBiochemistry

NanoFAST: Structure-based design of a small fluorogen-activating protein with only 98 amino acids

K. S. Mineev, S. A. Goncharuk, M. V. Goncharuk, N. V. Povarova, N. S. Baleeva, A. Y. Smirnov, I. N. Myasnyanko, D. A. Ruchkin, S. Bukhdruker, A. Remeeva, A. Mishin, V. Borshchevskiy, V. Gordeliy, A. S. Arseniev, D. A. Gorbachev, , M. S. Baranov

The paper designs a small fluorogen-activating protein (nanoFAST) by truncating FAST based on structural analysis, resulting in the shortest known genetically encoded tag with 98 amino acids.

bioRxiv · Dec 29, 2020Biochemistry