N. Tani

Somatic mutation rates scale with time not growth rate in long-lived tropical trees

This study finds that somatic mutation rates in tropical trees scale with time, not growth rate, showing a constant mutation rate per year across species with different growth rates.

EPI-589, a redox-active neuroprotectant, potently protects cultured cells from oxidative stress and alleviates symptomatic and pathological progression of motor neuron disease in the wobbler mouse

This study shows EPI-589, a redox-active compound, protects cells from oxidative stress and delays motor neuron disease symptoms in wobbler mice.

FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis

This study shows FBXO47 prevents premature disassembly of the synaptonemal complex in mouse male meiosis, ensuring proper synapsis and crossover formation.

Frequency band coupling with high-frequency activities during seizures shifts from θ band in tonic phase to δ band in clonic phase

This paper analyzes how high-frequency activities (HFAs) couple with low-frequency bands during seizures, finding that coupling shifts from theta to delta bands during the tonic to clonic phase.

High-quality SNPs from genic regions highlight introgression patterns among European white oaks (Quercus petraea and Q. robur).

This study challenges the 'allosteric switch' model of SHP2 activation by showing that the N-SH2 binding cleft is constitutively open in solution and its opening does not drive activation.

Cortisol levels adter cold exposure are independent of adrenocorticotropic hormone stimulation

This study shows that cortisol levels after cold exposure are not correlated with ACTH levels in human autopsies or in cell culture experiments.