N6-methyladenosine modification of HIV-1 RNA evades RIG-I-mediated sensing to suppresses type-I interferon induction in monocytic cells
S. Chen, S. Kumar, N. Tirumuru, J. L. Welch, L. Hu, C. He, J. T. Stapleton, L. Wu
This study shows that HIV-1 RNA's m6A modifications suppress type-I interferon induction in monocytic cells by evading RIG-I sensing.
bioRxiv · Nov 4, 2020Microbiology