P. C. Koneru

Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis

This study identifies three mechanisms by which class II HIV-1 integrase substitutions disrupt IN-RNA interactions, leading to virion maturation defects and premature viral genome degradation.

N6-methyladenosine Binding Proteins Negatively Regulate HIV-1 Infectivity and Viral Production

This study shows YTHDF1-3 proteins inhibit HIV-1 infection by binding m6A-modified viral RNA, reducing reverse transcription and viral production.