The Cystic Fibrosis treatment, Trikafta, affects growth, viability, and cell wall of Aspergillus fumigatus biofilms
J. T. Jones, K. A. Morelli, E. M. Vesely, C. Puerner, C. Pavuluri, B. S. Ross, N. v. Rhijn, M. J. Bromley, R. A. Cramer
This study shows Trikafta reduces A. fumigatus biofilm biomass, viability, and metabolic activity, while increasing susceptibility to antifungal drugs.
bioRxiv · Jun 20, 2023 · PreprintMicrobiology