Cancer BiologybioRxiv
β-catenin activity induces an RNA biosynthesis program promoting therapy resistance in T Acute Lymphoblastic Leukemia
V. Garcia-Hernandez, D. Arambilet, Y. Guillen…·A. Bigas
The paper identifies a β-catenin-regulated RNA biosynthesis program linked to therapy resistance in T-ALL and suggests combining chemotherapy with β-catenin inhibitors to improve treatment outcomes.
DOI 10.15252/emmm.202216554