Relocation of macrophages maintains the barrier function of the urothelium and protects against persistent infection
J. Bottek, C. Soun, J. K. Volke, A. Dixit, S. Thiebes, A.-L. Beerlage, M. Horstmann, A. Urbanek, J. Uszkoreit, M. Eisenacher, T. Bracht, B. Sitek, F. Hoffmann, N. Vijitha, F. von Eggeling, D. R. Engel
The paper shows that macrophage relocation into the urothelium, driven by IL-6 and CX3CL1, helps maintain barrier function and prevent recurrent urinary tract infections.
bioRxiv · Jun 6, 2019 · PreprintImmunology