Author

N. Winsor

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

D. J. Philpott· 1 shared J. Bruce· 1 shared L. Li· 1 shared S. E. Girardin· 1 shared S. Keely· 1 shared S. Tang· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

D. J. Philpott

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1 paper

Recent·Most cited

GSDMD pore formation regulates caspase-4 cleavage to limit IL-18 production in the intestinal epithelium

J. Bruce, L. Li, S. Tang, N. Winsor, S. Keely, D. J. Philpott, S. E. Girardin

This study shows that GSDMD pore formation stops caspase-4 activity to control IL-18 production in intestinal epithelial cells, preventing excessive inflammation.

bioRxiv · Feb 1, 2024 · PreprintCell Biology