Author

N. Y. Shpigel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

E. Nir· 2 shared E. Nissim-Eliraz· 2 shared N. Marsiano· 2 shared S. Yagel· 2 shared D. A. Rand· 1 shared D. Sela-Donenfeld· 1 shared E. Monsonego-Ornan· 1 shared F. Bergey· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

E. Nir

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MMP2 loss leads to defective parturition and severe dystocia in mice

R. Kalev-Altman, T. Levy, N. Y. Shpigel, E. Monsonego-Ornan, D. Sela-Donenfeld

This study shows that MMP2 loss causes dystocia and uterine fibrosis in mice, highlighting its role in parturition.

bioRxiv · Nov 22, 2022 · PreprintPhysiology

Hyperinflammation evokes different antiviral TMPRSS2 and ADAM17 expression responses in human gut xenograft versus host mouse gut although overall genomic responses are similar

L. Morris, E. Nissim-Eliraz, I. Schouten, F. Bergey, N. Dyer, H. Momiji, E. Nir, N. Marsiano, R. S. Tezerji, S. Yagel, P. Rosenstiel, D. A. Rand, V. A. P. Martins dos Santos, N. Y. Shpigel, SysmedIBD research consortium

This study compares antiviral gene expression responses in human gut xenografts and host mouse gut during hyperinflammation, finding similar genomic responses but species-specific upregulation of TMPRSS2 and ADAM17 in human gut.

bioRxiv · May 9, 2021 · PreprintImmunology

NF-kappa-B activation unveils the presence of inflammatory hotspots in human gut xenografts

E. Nissim-Eliraz, E. Nir, N. Marsiano, S. Yagel, N. Y. Shpigel

This study visualizes and quantifies NF-kappa-B activity in human gut xenografts, revealing discrete inflammatory hotspots in both steady state and inflamed conditions.

bioRxiv · Jul 23, 2020Immunology