Molecular BiologyCell ReportsPeer-reviewed
Proximity determines donor candidacy during DNA double-stranded break homology directed repair
Charles D. Yeh, Lilly van de Venn, Susanne Kreutzer…·Jacob E. Corn
The paper develops RaPID-seq to study homology search during HDR and finds that DSB proximity determines template candidacy, with distant sequences not efficiently searched despite sequence identity.
DOI 10.1016/j.celrep.2026.117864