Dystrophin Dp71 is essential for the development and function of macrophages
Natalia Chira, Julian Swatler, Antigoni Manousopoulou, Robin M. H. Rumney, Jacek Hajto, Aleksandra Oksiejuk, Diana Garay Baquero, Justyna Róg, Cory White, Stefan Hinz, Nancy Alnassar, Christopher Young, S. Arkle, Michał Korostyński, Ewa Kozłowska, , Dariusz C. Górecki
This study shows that Dp71 dystrophin is essential for macrophage development and function, as its absence disrupts migration, phagocytosis, and inflammasome activity in mouse macrophages.
bioRxiv · Apr 24, 2025 · PreprintCell Biology